李建科
李建科，男，教授（2级），博士生导师，蜜蜂饲养与生物技术研究室主任，国家现代蜂产业技术体系岗位科学家，曾主持完成国家自然基金，参加“十一五”“十二五”支撑项目，农业行业科研专项等项目。主要从事蜜蜂饲养技术与蜜蜂蛋白质组学研究。近年来在蛋白质组学国际重要学术期刊，如 《Molecular & Cellular proteomics》，《Journal of Proteome Research》，《Journal of Proteomics》等杂志发表论文30多篇，累积影响因子140以上。同时也是Journal of Proteome Research，Journal of Proteomics, BMC Genomics, Apidologie，Insect molecular biology等国际学术期刊的论文评阅人。培养研究生20多人（其中留学生5人），所指导博士研究生曾获“国家奖学金”和中国农业科学院优秀博士论文培养对象，硕士研究生获“省级优秀论文”。
发表论文：
1. Bin Han, Yu Fang, Mao Feng, Xiaoshan Lu, Xinmei Huo, Lifeng Meng, Bin Wu and Jianke Li. In-depth Phosphoproteomic Analysis of Royal Jelly Derived from Western and Eastern Honeybee Species. J Proteome Res. In press (IF 5.1).
2. Yu Fang, Mao Feng, Bin Han, XiaoShan Lu, Haitham Ramadan, Jianke Li. In-depth Proteomics Characterization of Embryogenesis of the Honey Bee Worker (Apis mellifera L.). Mol Cell Proteomics. 2014, 13 (9): 2306-2320. (IF 7.25)
3. Mao Feng, Haitham Ramadan, Bin Han, Yu Fang and Jianke Li. Hemolymph proteome changes during worker brood development match the biological divergences between western honey bees (Apis mellifera) and eastern honey bees (Apis cerana). BMC Genomics, 2014, 2014, 15:563 (IF 4.4).
4. Lan Zhang, Bin Han, Rongli Li, Xiaoshan Lu, Yu Fang, Mao Feng, Jianke Li.. Comprehensive identification of novel proteins and N-glycosylation sites in royal jelly. BMC Genomics, 2014,15(1):135. (IF 4.4)
5. Rongli Li, Lan Zhang, Yu Fang, Bin Han, Xiaoshan Lu, Tiane Zhou, Mao Feng, Jianke Li. Proteome and phosphoproteome analysis of honeybee (Apis mellifera) venom collected from electrical stimulation and manual extraction of the venom gland. BMC genomics, 2013, 14(1),766. (IF 4.4)
6. Alemayehu Gala, Yu Fang, Dereje Woltedji, Lan Zhang, Bin Han, Mao Feng, Jianke Li. Changes of Proteome and Phosphoproteome Trigger Embryo-larva Transition of Honeybee Worker (Apis mellifera ligustica). J Proteomics. 2013, 78, 428-46. (IF 4.9)
7. Bin Han, Lan Zhang, Mao Feng, Yu Fang, Jianke Li. An Integrated Proteomics Reveals Pathological Mechanism of Honeybee (Apis cerena) Sacbrood Disease. J Proteome Res. 2013, 12, 1881-97. (IF 5.1)
8. Dereje Woltedji, Yu Fang, Bin Han, Mao Feng, Rongli Li, Alemayehu Gala, Jianke Li. Proteome Analysis of Hemolymph Changes during the Larval to Pupal Development Stages ofHoneybee Workers (Apis mellifera ligustica). J Proteome Res. 2013, 12(11), 5189-98. (IF 5.1)
9. Mao Feng, Yu Fang, Bin Han, Lan Zhang, Xiaoshan Lu, Jianke Li. Novel aspects of understanding molecular working mechanisms of salivary glands of worker honeybees (Apis mellifera) investigated by proteomics and phosphoproteomics. J Proteomics. 2013; 87, 1-15. (IF 4.1)
10. Li, HL; Zhang, LY ; Ni, CX ; Shang, HW ; Zhuang, SL ; Li, JK. Molecular recognition of floral volatile with two olfactory related proteins in the Eastern honeybee (Apis cerana). Int J Biol Macromol, 2013, 56: 114-21. (IF 2.6)
11. Desalegn Begna, Bin Han, Mao Feng, Yu Fang, Jianke Li. Differential Expressions of Nuclear Proteomes between Honeybee (Apis mellifera L.) Queen and Worker Larvae: A Deep Insight into Caste Pathway Decisions. J. Proteome Res. 2012, 11 (2), 1317-29. (IF 5.1)
12. Woltedji Dereje, Song Feifei, Zhang Lan, Alemayehu Gala, Han Bin, Feng Mao, Fang Yu, Jianke Li. Western Honeybee Drones and Workers (Apis mellifera ligustica) Have Different Olfactory Mechanisms than Eastern Honeybees (Apis cerana cerana). J Proteome Res. 2012, 11, 4526-40. (IF 5.1)
13. Lan Zhang, Yu Fang, Rongli Li, Mao Feng, Bin Han, Tiane Zhou, Jianke Li. Towards posttranslational modification proteome of royal jelly. J Proteomics. 2012 ,75, 5327-41. (IF 4.9)
14. Yu Fang, Feifei Song, Lan Zhang, Dereje Woltedji, Bin Han, Mao Feng, Jianke Li. Differential antennal proteome comparison of adult honeybee drone, worker and queen (Apis mellifera L.). J. Proteomics, 2012, 75, 756-73. (IF 4.9)
15. Desalegn Begna, Yu Fang, Mao Feng, Jianke Li. Mitochondrial Proteins Differential Expression during Honeybee (Apis mellifera L.) Queen and Worker Larvae Caste Determination. J. Proteome Res. 2011, 10(9):4263-80. (IF 5.46)
16. Mao Feng, Feifei Song, Dereje Woltedji Aleku, Bin Han, Yu Fang, Jianke Li. Antennal Proteome Comparison of Sexually Mature Drone and Forager Honeybees. J. Proteome Res. 2011, 10(7):3246-60. (IF 5.46)
17. Aijuan Zheng, Jianke Li, Desalegn Begna, Yu Fang, Mao Feng, Feifei Song. Proteomic Analysis of Honeybee (Apis mellifera L.) Pupae Head Development. PLoS ONE, 2011, 6(5): e20428. (IF 4.4)
18. Jianke Li, Yu Fang, Lan Zhang, Desalegn Begna. Honeybee (Apis mellifera ligustica) drone embryo proteomes. J. Insect Physiol, 2011, 57 (3), 372-84. (IF 2.31)
19. Bin Han, Chenxi Li, Lan Zhang, Yu Fang, Mao Feng, Jianke Li. Novel Royal Jelly Proteins Identified by Gel-Based and Gel-free Proteomics. J. Agric. Food Chem. 2011; 59(18):10346-55. (IF 2.816)
20. Yu Fang, Mao Feng, Jianke Li,. Royal jelly proteome comparison between A. mellifera ligustica and A. cerana cerana. J.Proteome Res. 2010, 9(5):2207-15. (IF 5.132)
21. Jianke Li, Mao Feng, Desalegn Begna, Yu Fang. Proteome comparison of hypopharyngeal gland development between Italian and royal jelly producing worker honeybees (Apis mellifera L.). J.Proteome Res. 2010, 9(12), 6578-94. (IF 5.132)
22. Jianke Li, Jing Wu, Desalegn Begna, Feifei Song, Aijuan Zheng, Yu Fang. Differential Protein Expression in Honeybee (Apis mellifera L.) Larvae: Underlying Caste Differentiation. PLoS ONE, 2010, 5(10): e13455. (IF 4.35)
23. Jianke Li, Mao Feng, Lan Zhang, Yinghong Pan. Proteomics analysis of major royal jelly protein changes under different storage conditions. J. Proteome Res. 2008, 7 (8), 3339–3353. (IF 5.675)
24. Jianke Li, Lan Zhang, Mao Feng, Zhaohui Zhang,Yinghong Pan. Identification of the proteome composition occurring during the course of embryonic development of bees (Apis mellifera). Insect Mol Biol., 2009,18 (1): 1-9. (IF 2.787)
25. Mao Feng, Yu Fang, Jianke Li. Proteomic analysis of honeybee worker (Apis mellifera) hypopharyngeal gland development. BMC Genomics. 2009,10: 645. (IF 4.07)
26. Jianke Li, Jian Chen, Zhao-hui Zhang, Ying-hong Pan. Proteome Analysis of Tea Pollen (Camellia sinensis) under Different Storage Conditions. J. Agric. Food Chem. 2008, 56, 7535-44. (IF 2.532)
27. Jianke Li, Ting Wang, Zhaohui Zhang,Yinghong Pan. Proteomic Analysis of Royal Jelly from Three Strains of Western Honeybees (Apis mellifera). J. Agric. Food Chem. 2007, 55, 8411-22. (IF 2.322)
28. Jianke Li; Ting Wang. Comparative analysis of the effects of different storage conditions on major royal jelly proteins. J. Apicul. Res. 2007, 46: 73-80. (IF 0.75)
29. Jianke Li, Huawei Li, Zhaohui Zhang,Yinghong Pan. Identification of the proteome complement of the higher royal jelly producing bees (Apis mellifera L.) during the worker larvae development. Apidologie, 2007, 38(6): 545-557. (IF 2.2)
30. Jianke Li, Mao Feng, Zhaohui Zhang,Yinghong Pan. Identification of proteome complement of hypopharyngeal gland from two species of worker bees (Apis mellifera) in winter. Apidologie. 2008, 39(2): 199-214. (IF 2.2)
发表论文：
1. Bin Han, Yu Fang, Mao Feng, Xiaoshan Lu, Xinmei Huo, Lifeng Meng, Bin Wu and Jianke Li. In-depth Phosphoproteomic Analysis of Royal Jelly Derived from Western and Eastern Honeybee Species. J Proteome Res. In press (IF 5.1).
2. Yu Fang, Mao Feng, Bin Han, XiaoShan Lu, Haitham Ramadan, Jianke Li. In-depth Proteomics Characterization of Embryogenesis of the Honey Bee Worker (Apis mellifera L.). Mol Cell Proteomics. 2014, 13 (9): 2306-2320. (IF 7.25)
3. Mao Feng, Haitham Ramadan, Bin Han, Yu Fang and Jianke Li. Hemolymph proteome changes during worker brood development match the biological divergences between western honey bees (Apis mellifera) and eastern honey bees (Apis cerana). BMC Genomics, 2014, 2014, 15:563 (IF 4.4).
4. Lan Zhang, Bin Han, Rongli Li, Xiaoshan Lu, Yu Fang, Mao Feng, Jianke Li.. Comprehensive identification of novel proteins and N-glycosylation sites in royal jelly. BMC Genomics, 2014,15(1):135. (IF 4.4)
5. Rongli Li, Lan Zhang, Yu Fang, Bin Han, Xiaoshan Lu, Tiane Zhou, Mao Feng, Jianke Li. Proteome and phosphoproteome analysis of honeybee (Apis mellifera) venom collected from electrical stimulation and manual extraction of the venom gland. BMC genomics, 2013, 14(1),766. (IF 4.4)
6. Alemayehu Gala, Yu Fang, Dereje Woltedji, Lan Zhang, Bin Han, Mao Feng, Jianke Li. Changes of Proteome and Phosphoproteome Trigger Embryo-larva Transition of Honeybee Worker (Apis mellifera ligustica). J Proteomics. 2013, 78, 428-46. (IF 4.9)
7. Bin Han, Lan Zhang, Mao Feng, Yu Fang, Jianke Li. An Integrated Proteomics Reveals Pathological Mechanism of Honeybee (Apis cerena) Sacbrood Disease. J Proteome Res. 2013, 12, 1881-97. (IF 5.1)
8. Dereje Woltedji, Yu Fang, Bin Han, Mao Feng, Rongli Li, Alemayehu Gala, Jianke Li. Proteome Analysis of Hemolymph Changes during the Larval to Pupal Development Stages ofHoneybee Workers (Apis mellifera ligustica). J Proteome Res. 2013, 12(11), 5189-98. (IF 5.1)
9. Mao Feng, Yu Fang, Bin Han, Lan Zhang, Xiaoshan Lu, Jianke Li. Novel aspects of understanding molecular working mechanisms of salivary glands of worker honeybees (Apis mellifera) investigated by proteomics and phosphoproteomics. J Proteomics. 2013; 87, 1-15. (IF 4.1)
10. Li, HL; Zhang, LY ; Ni, CX ; Shang, HW ; Zhuang, SL ; Li, JK. Molecular recognition of floral volatile with two olfactory related proteins in the Eastern honeybee (Apis cerana). Int J Biol Macromol, 2013, 56: 114-21. (IF 2.6)
11. Desalegn Begna, Bin Han, Mao Feng, Yu Fang, Jianke Li. Differential Expressions of Nuclear Proteomes between Honeybee (Apis mellifera L.) Queen and Worker Larvae: A Deep Insight into Caste Pathway Decisions. J. Proteome Res. 2012, 11 (2), 1317-29. (IF 5.1)
12. Woltedji Dereje, Song Feifei, Zhang Lan, Alemayehu Gala, Han Bin, Feng Mao, Fang Yu, Jianke Li. Western Honeybee Drones and Workers (Apis mellifera ligustica) Have Different Olfactory Mechanisms than Eastern Honeybees (Apis cerana cerana). J Proteome Res. 2012, 11, 4526-40. (IF 5.1)
13. Lan Zhang, Yu Fang, Rongli Li, Mao Feng, Bin Han, Tiane Zhou, Jianke Li. Towards posttranslational modification proteome of royal jelly. J Proteomics. 2012 ,75, 5327-41. (IF 4.9)
14. Yu Fang, Feifei Song, Lan Zhang, Dereje Woltedji, Bin Han, Mao Feng, Jianke Li. Differential antennal proteome comparison of adult honeybee drone, worker and queen (Apis mellifera L.). J. Proteomics, 2012, 75, 756-73. (IF 4.9)
15. Desalegn Begna, Yu Fang, Mao Feng, Jianke Li. Mitochondrial Proteins Differential Expression during Honeybee (Apis mellifera L.) Queen and Worker Larvae Caste Determination. J. Proteome Res. 2011, 10(9):4263-80. (IF 5.46)
16. Mao Feng, Feifei Song, Dereje Woltedji Aleku, Bin Han, Yu Fang, Jianke Li. Antennal Proteome Comparison of Sexually Mature Drone and Forager Honeybees. J. Proteome Res. 2011, 10(7):3246-60. (IF 5.46)
17. Aijuan Zheng, Jianke Li, Desalegn Begna, Yu Fang, Mao Feng, Feifei Song. Proteomic Analysis of Honeybee (Apis mellifera L.) Pupae Head Development. PLoS ONE, 2011, 6(5): e20428. (IF 4.4)
18. Jianke Li, Yu Fang, Lan Zhang, Desalegn Begna. Honeybee (Apis mellifera ligustica) drone embryo proteomes. J. Insect Physiol, 2011, 57 (3), 372-84. (IF 2.31)
19. Bin Han, Chenxi Li, Lan Zhang, Yu Fang, Mao Feng, Jianke Li. Novel Royal Jelly Proteins Identified by Gel-Based and Gel-free Proteomics. J. Agric. Food Chem. 2011; 59(18):10346-55. (IF 2.816)
20. Yu Fang, Mao Feng, Jianke Li,. Royal jelly proteome comparison between A. mellifera ligustica and A. cerana cerana. J.Proteome Res. 2010, 9(5):2207-15. (IF 5.132)
21. Jianke Li, Mao Feng, Desalegn Begna, Yu Fang. Proteome comparison of hypopharyngeal gland development between Italian and royal jelly producing worker honeybees (Apis mellifera L.). J.Proteome Res. 2010, 9(12), 6578-94. (IF 5.132)
22. Jianke Li, Jing Wu, Desalegn Begna, Feifei Song, Aijuan Zheng, Yu Fang. Differential Protein Expression in Honeybee (Apis mellifera L.) Larvae: Underlying Caste Differentiation. PLoS ONE, 2010, 5(10): e13455. (IF 4.35)
23. Jianke Li, Mao Feng, Lan Zhang, Yinghong Pan. Proteomics analysis of major royal jelly protein changes under different storage conditions. J. Proteome Res. 2008, 7 (8), 3339–3353. (IF 5.675)
24. Jianke Li, Lan Zhang, Mao Feng, Zhaohui Zhang,Yinghong Pan. Identification of the proteome composition occurring during the course of embryonic development of bees (Apis mellifera). Insect Mol Biol., 2009,18 (1): 1-9. (IF 2.787)
25. Mao Feng, Yu Fang, Jianke Li. Proteomic analysis of honeybee worker (Apis mellifera) hypopharyngeal gland development. BMC Genomics. 2009,10: 645. (IF 4.07)
26. Jianke Li, Jian Chen, Zhao-hui Zhang, Ying-hong Pan. Proteome Analysis of Tea Pollen (Camellia sinensis) under Different Storage Conditions. J. Agric. Food Chem. 2008, 56, 7535-44. (IF 2.532)
27. Jianke Li, Ting Wang, Zhaohui Zhang,Yinghong Pan. Proteomic Analysis of Royal Jelly from Three Strains of Western Honeybees (Apis mellifera). J. Agric. Food Chem. 2007, 55, 8411-22. (IF 2.322)
28. Jianke Li; Ting Wang. Comparative analysis of the effects of different storage conditions on major royal jelly proteins. J. Apicul. Res. 2007, 46: 73-80. (IF 0.75)
29. Jianke Li, Huawei Li, Zhaohui Zhang,Yinghong Pan. Identification of the proteome complement of the higher royal jelly producing bees (Apis mellifera L.) during the worker larvae development. Apidologie, 2007, 38(6): 545-557. (IF 2.2)
30. Jianke Li, Mao Feng, Zhaohui Zhang,Yinghong Pan. Identification of proteome complement of hypopharyngeal gland from two species of worker bees (Apis mellifera) in winter. Apidologie. 2008, 39(2): 199-214. (IF 2.2)